| lovepopOther | Other | Cambridge, United States | Wombi Rose | lovepopcards.com |
| LovysFintech | Fintech | Paris, France | João Cardoso | lovys.com |
| LoyalHealthcare | Healthcare | — | Cate Luzio | loyal.com |
| LP PortalOther | Other | — | — | adfs4.sts.altareturn.com |
| LuaConsumer | Consumer | New York City, United States | — | getlua.com |
| Lua Global IncB2B | B2B | — | | heylua.ai |
| LucentB2B | B2B | — | Alisa Rae | lucenthq.com |
| LucisHealthcare | Healthcare | Paris, France | | lucis.life |
| Lucky JuiceboxOther | Other | San Francisco, United States | — | luckyjuicebox.com |
| LuelB2B | B2B | — | | luel.ai |
| LullaaiOther | Other | Madrid, Spain | — | lullaai.com |
| LumariB2B | B2B | San Francisco, United States | | lumari.io |
| LumeonHealthcare | Healthcare | Boston, United States | Robbie Hughes | lumeon.com |
| LuminaDataB2B | B2B | San Jose, United States | — | luminadata.ai |
| LuminalB2B | B2B | — | | luminal.com |
| Lumos HelmetOther | Other | Boston, United States | Eu-wen Ding | lumoshelmet.co |
| LunaBillHealthcare | Healthcare | San Francisco, United States | | lunabill.com |
| LunarCrushB2B | B2B | Costa Mesa, United States | Joe Vezzani | lunarcrush.com |
| LunasondeIndustrials | Industrials | Cortaro, United States | — | lunasonde.com |
| LunavoB2B | B2B | San Francisco, United States | | lunavo.ai |
| Lupin & HolmesB2B | B2B | — | — | landh.tech |
| Lux SemiconductorsOther | Other | Albany, United States | — | luxsemiconductors.com |
| LynqOther | Other | New York City, United States | — | lynqnetworks.com |
| LyraB2B | B2B | San Francisco, United States | | lyra.so |
| MachinationsB2B | B2B | — | Paul Bragiel | machinations.io |
| Machinery PartnerOther | Other | Boston, United States | Benedikt Franke | machinerypartner.com |
| MadKuduB2B | B2B | Mountain View, United States | Francis Brero | madkudu.com |
| Mae - Making Auto EasyIndustrials | Industrials | Richmond, Canada | — | makingautoeasy.com |
| MagneticB2B | B2B | — | | magnetictax.com |
| MagnitudeB2B | B2B | San Francisco, United States | | magnitude.dev |
| MainframeFintech | Fintech | San Francisco, United States | Mick Hagen | mainframe.co |
| MainstayB2B | B2B | Arlington, United States | Drew Magliozzi | admithub.com |
| Maiven EnergyB2B | B2B | Boulder, United States | — | askmaiven.com |
| make-tutoB2B | B2B | Tel Aviv, Israel | — | tutoit.io |
| MakeswiftOther | Other | Atlanta, United States | Robert Vogt | makeswift.com |
| ManaraB2B | B2B | — | Laila Arafeh | manara.tech |
| ManateeOther | Other | Denver, United States | Tara Vaysman | getmanatee.com |
| Mango MedicalHealthcare | Healthcare | — | | mangomedical.io |
| MangoDeskB2B | B2B | San Francisco, United States | | mangodesk.com |
| Mani.MeOther | Other | Palo Alto, United States | Michelle Lam | manime.co |
| ManiculeB2B | B2B | San Francisco, United States | Naman Bansal | manicule.dev |
| MantisB2B | B2B | — | | mantisbiotech.com |
| MANTLFintech | Fintech | New York City, United States | Nathaniel Harley | mantl.com |
| MantleB2B | B2B | — | | mantle.work |
| Manufact (formerly mcp-use)B2B | B2B | — | | manufact.com |
| MapkinConsumer | Consumer | Cambridge, United States | — | mapkin.co |
| MapYourPropertyOther | Other | Toronto, Canada | — | mapyourproperty.com |
| Maquoketa ResearchIndustrials | Industrials | — | | maquoketa.net |
| Marble ARFintech | Fintech | Los Angeles, United States | — | marblever.se |
| Marcopolo LearningConsumer | Consumer | — | — | marcopololearning.com |