| SorceB2B | B2B | San Francisco, United States | | sorce.jobs |
| SourcebotB2B | B2B | San Francisco, United States | | sourcebot.dev |
| SparklesB2B | B2B | — | | sparkles.dev |
| Spatial AIB2B | B2B | Palo Alto, United States | | spatial-ai.com |
| SpecificB2B | B2B | Stockholm, Sweden | | specific.dev |
| SpongeB2B | B2B | — | | paysponge.com |
| Spotlight RealtyOther | Other | New York, United States | | spotlight.realty |
| SpotPayFintech | Fintech | — | Zsika Phillip | spotpay.ai |
| SquidIndustrials | Industrials | — | | squid.energy |
| StageB2B | B2B | — | | stagereview.app |
| StandoutConsumer | Consumer | San Francisco, United States | | standout.work |
| StarSlingB2B | B2B | San Francisco, United States | | starsling.dev |
| Stellon LabsB2B | B2B | San Francisco, United States | | stellonlabs.com |
| StiltaB2B | B2B | — | | stilta.com |
| StocklineB2B | B2B | San Francisco, United States | | stockline.ai |
| Strand AIHealthcare | Healthcare | — | Yue Dai | strandai.com |
| Structured AIOther | Other | New York, United States | Raymond Zhao | getstructured.ai |
| SunflowerConsumer | Consumer | — | | sunflowersober.com |
| SupersetB2B | B2B | — | | superset.sh |
| SureformB2B | B2B | Palo Alto, United States | | sureformhq.com |
| Sygaldry TechnologiesIndustrials | Industrials | — | | sygaldry.com |
| Synthetic SciencesB2B | B2B | — | | syntheticsciences.ai |
| Synthetic SocietyB2B | B2B | San Francisco, United States | | syntheticsociety.ai |
| SyntropyB2B | B2B | — | | syntropy.io |
| Talking ComputersB2B | B2B | — | | talkingcomputers.ai |
| TectoAIB2B | B2B | San Francisco, United States | Niosha Afsharikia, PhD | tecto.ai |
| TelemetronB2B | B2B | — | | telemetron.ai |
| TensrIndustrials | Industrials | San Francisco, United States | | tensr.com |
| TepaliB2B | B2B | — | | tepali.com |
| Terminal UseB2B | B2B | — | | terminaluse.com |
| Terranox AIIndustrials | Industrials | — | | terranox.ai |
| TesoraB2B | B2B | — | Vivek Rao | tesora.ai |
| TesterArmyB2B | B2B | San Francisco, United States | Oskar Kwaśniewski | tester.army |
| Text.aiConsumer | Consumer | San Francisco, United States | | text.ai |
| TheoremB2B | B2B | San Francisco, United States | | theorem.dev |
| ThesisB2B | B2B | San Francisco, United States | | thesislabs.ai |
| ThetaB2B | B2B | San Francisco, United States | | thetasoftware.com |
| Third ChairB2B | B2B | San Francisco, United States | | usethirdchair.com |
| Ticket WalletB2B | B2B | — | | ticketwallet.com |
| TopologicalB2B | B2B | — | | topological.com |
| TornyolConsumer | Consumer | — | | tornyol.com |
| TraceB2B | B2B | San Francisco, United States | | trace.so |
| TraceRoot.AIB2B | B2B | — | | traceroot.ai |
| TraverseB2B | B2B | — | | traverse.so |
| TravoOther | Other | — | | travoai.com |
| TsentaConsumer | Consumer | — | | tsenta.com |
| UnifoldFintech | Fintech | — | | unifold.io |
| UnissonB2B | B2B | — | Varun Mathur | unisson.ai |
| Unsiloed AIB2B | B2B | San Francisco, United States | Aman Mishra | unsiloed.ai |
| UplaneB2B | B2B | San Francisco, United States | Julius Körfgen | uplane.com |