| RevionB2B | B2B | — | | revion.inc |
| Rhizome AIB2B | B2B | — | | rhizomeai.com |
| RimbaIndustrials | Industrials | San Francisco, United States | | rimba.ai |
| Risely AIEducation | Education | — | | risely.ai |
| RitivelHealthcare | Healthcare | San Francisco, United States | | ritivel.com |
| RiverbankB2B | B2B | San Francisco, United States | | riverbank.sh |
| RivetB2B | B2B | San Francisco, United States | | rivet.design |
| RobbyB2B | B2B | — | Vineet Jammalamadaka | tryrobby.com |
| RoboDockIndustrials | Industrials | — | | robodock.tech |
| Rovi HealthHealthcare | Healthcare | New York, United States | | rovi.health |
| RovrB2B | B2B | San Francisco, United States | | withrovr.com |
| RowFlowB2B | B2B | New York, United States | | rowflow.ai |
| Rubric AIB2B | B2B | — | | therubric.ai |
| Ruma CareHealthcare | Healthcare | — | | rumacare.com |
| RunAnywhereB2B | B2B | — | | runanywhere.ai |
| RunRLB2B | B2B | San Francisco, United States | | runrl.com |
| RuntimeB2B | B2B | San Francisco, United States | | runtm.com |
| RuvoFintech | Fintech | São Paulo, Brazil | | ruvo.com |
| SaffronB2B | B2B | San Francisco, United States | | trysaffron.ai |
| Saffron HealthHealthcare | Healthcare | — | Tanishq Kancharla | saffron.health |
| SalusB2B | B2B | San Francisco, United States | | usesalus.ai |
| Samora AIB2B | B2B | — | | samora.ai |
| SavaFintech | Fintech | — | Nimit Maru | savahq.com |
| SazabiB2B | B2B | San Francisco, United States | | sazabi.com |
| Scalar FieldFintech | Fintech | — | | scalarfield.io |
| Scheduling WizardHealthcare | Healthcare | — | | schedulingwiz.com |
| SciloopB2B | B2B | San Francisco, United States | | sciloop.dev |
| ScoopB2B | B2B | San Francisco, United States | | scooplabs.ai |
| Scott AIB2B | B2B | New York, United States | | tryscott.ai |
| Scout OutOther | Other | — | | scoutout.ai |
| Seeing SystemsIndustrials | Industrials | — | | seeing-systems.com |
| SelfinFintech | Fintech | San Francisco, United States | | selfin.app |
| SellRazeConsumer | Consumer | San Francisco, United States | | sellraze.com |
| Semble AIB2B | B2B | San Francisco, United States | | sembleai.com |
| SemioticB2B | B2B | San Francisco, United States | | semiotic.com |
| SentrialB2B | B2B | — | | sentrial.com |
| Sequence MarketsFintech | Fintech | — | | sequencemkts.com |
| Servo7Industrials | Industrials | — | | servo7.com |
| SF TensorB2B | B2B | — | | sf-tensor.com |
| ShofoB2B | B2B | — | | shofo.ai |
| ShorFintech | Fintech | San Francisco, United States | Daivik Goel | tryshor.com |
| SigmanticAIB2B | B2B | Dublin, United States | | sigmanticai.com |
| SilaB2B | B2B | — | | silahq.com |
| SiraB2B | B2B | — | | sira.team |
| SkillsyncB2B | B2B | — | Narayana Aaditya Ganeshkumar | skillsync.wiki |
| SkopeB2B | B2B | San Francisco, United States | | useskope.com |
| SlashyB2B | B2B | San Francisco, United States | | slashy.com |
| Socratix AIB2B | B2B | — | | getsocratix.ai |
| SolvaFintech | Fintech | — | | solvatechnology.com |
| SonarlyB2B | B2B | — | | sonarly.com |